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일반적으로 오심, 구토 위장질환, 심장질환 등..

니코틴 드링크제가 할일없어 의약품으로 안나온게 아니다.


NICOTINE

Clinical Effects
CNS toxicity includes sympathetic, parasympathetic or neuromuscular effects. COMMON: N/V, abdominal pain, salivation, tachypnea, hypertension, tachycardia, SEVERE: confusion, agitation/restlessness, lethargy, seizures, coma, dysrhythmias, hypotension, rhabdomyolysis, electrolyte imbalance. ABSORPTION: after ingestion, inhalation, dermal, or rectal exposure. DURATION: Mild: 1-2 hours; Severe: 8-24 hours.

Treatment
Decontamination: Emesis is usually spontaneous; do NOT induce. Activated charcoal, gastric lavage.
Seizure: IV benzodiazepines, barbiturates
Hypotensive episode: IV 0.9% NaCl, dopamine, norepinephrine.
Rhabdomyolysis: IV hydration, adequate urine output.
Monitoring of patient: Monitor vital signs, electrolytes, ECG, and neurolgic function.

Range Of Toxicity
Ingestion of 1 fresh cigarette, 3 "butts", 1 pinch of snuff, or any amount of gum is potentially toxic. ADULT - 2 to 5 mg can cause nausea, estimated lethal oral dose is 40 to 60 mg; CHILD - 1 mg can produce symptoms in a small child, 1.4 mg/kg may cause severe toxicity.


Cardiovascular Effects
Angina pectoris
Cardiovascular finding
Hypertension
Myocardial infarction
Tachyarrhythmia

Dermatologic Effects
Dermatological finding
Skin irritation

Endocrine/Metabolic Effects
Body temperature finding
Hot flash

Gastrointestinal Effects
Abdominal discomfort
Chalasia of lower esophageal sphincter
Diarrhea
Dyspepsia
Gastrointestinal tract finding
Nausea
Xerostomia

Musculoskeletal Effects
Musculoskeletal finding
Myasthenia gravis, Exacerbation

Neurologic Effects
Cerebrovascular accident
Dizziness
Headache
Lightheadedness
Neurological finding
Nystagmus

Ophthalmic Effects
Eye / vision finding
Finding of lacrimation

Psychiatric Effects
Depression
Dyssomnia
Psychiatric sign or symptom

Respiratory Effects
Bronchitis
Cough
Exacerbation of asthma
Respiratory finding
Rhinitis
Throat irritation

Other
Summary
Drug dependence
Drug withdrawal
Hiccoughs
Toxic effect of tobacco and nicotine, Green tobacco sickness